Merck recalls batches of Hib vaccines

Merck has recalled batches of two childhood vaccines, PedvaxHIB and Comvax, which protect against Haemophilus influenzae type b (Hib). During routine testing, Merck found Bacillus cereus bacteria that had survived sterilisation of its manufacturing equipment, although no contamination was found in the finished vaccines. Bacillus cereus is a food-borne bacterium normally found in soil, vegetables […]

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Stop deferasirox if liver enzymes rise

Novartis has strengthened its warnings about possible liver failure during treatment with deferasirox (Exjade), an iron-chelating medicine used to remove excess iron, for example in people who have frequent blood transfusions. The company stresses that the dose should be adjusted, or treatment stopped, if blood levels of liver enzymes (transaminases) rise. Patients on deferasirox need […]

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First medicine approved for phenylketonuria

The US Food and Drug Administration (FDA) has approved a medicine containing sapropterin dihydrochloride to treat phenylketonuria (PKU). PKU is an inherited metabolic disorder that can cause learning disability and various nerve problems. It is caused by a missing or faulty enzyme, phenylalanine hydroxylase, which normally breaks down phenylalanine and so keeps its level in […]

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Is bypass surgery better than angioplasty?

A review shows that patients with moderate coronary artery disease are more likely to be free of recurring angina if they have bypass surgery rather than balloon angioplasty, with or without a stent. Moderate disease was defined as one blockage in the vital left anterior descending artery, two blockages, or in some less severe cases […]

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Medical errors by doctors in training

In a study for the US Agency for Healthcare Research and Quality (AHRQ), researchers at the University of Texas, the University of Houston and Harvard University analysed a random sample of 889 malpractice claims from 2002 to 2004 to find out why medical errors happen. They looked at whether the errors really occurred or were […]

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Pfizer stops selling inhaled insulin

Pfizer has announced that it will stop making and selling Exubera, its inhaled insulin, 15 months after it went on sale. "Despite all our efforts, Exubera has not gained the acceptance of patients and doctors we had hoped for, so we are ending our investment in it," said chief executive Jeff Kindler. Few doctors prescribed […]

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A designer oestrogen may protect the brain

Scientists at the University of California, Los Angeles (UCLA) have found the first evidence that a specific form of oestrogen can protect the brain in multiple sclerosis without raising the risk of oestrogen-driven cancers such as breast and womb cancer, and that men could use it without the side effects of traditional oestrogen. The study […]

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