Exercise reduces the risk of heart disease

In a study of 27,000 women followed for 11 years, researchers assessed various risk factors at different levels of physical activity. "Regular exercise has a big effect in preventing strokes and heart disease," says Dr Samia Mora of Harvard Medical School. The changes in risk factors such as blood pressure and inflammation explained part of […]

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Do flu vaccines save the lives of older people?

Vaccinating older people against flu should reduce hospital admissions and deaths, but earlier studies struggled to show this: although vaccination of older people rose from 15% in 1980 to 65% in the mid-1990s, no clear fall in deaths was seen. Most Western countries still recommend vaccinating all older people, partly because it would be unethical […]

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Combining medicines is the best strategy against rheumatoid arthritis

According to the US Agency for Healthcare Research and Quality (AHRQ), combining a well-known, inexpensive synthetic medicine with one of the six biological medicines works best to reduce joint swelling and tenderness in rheumatoid arthritis. The review compared synthetic disease-modifying anti-rheumatic drugs (DMARDs): hydroxychloroquine, leflunomide, methotrexate and sulfasalazine; biological DMARDs: abatacept, adalimumab, anakinra, etanercept, infliximab […]

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Aprotinin linked with higher death rates

Bayer, maker of Trasylol (aprotinin), announced that a Canadian study had found preliminary evidence that patients having heart surgery were more likely to die within 30 days if they received aprotinin rather than other medicines used to reduce blood loss after surgery. The study, called Blood Conservation Using Antifibrinolytics in a Randomized Trial (BART), aimed […]

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Raltegravir approved to treat HIV

The US Food and Drug Administration (FDA) has approved raltegravir tablets (Isentress) for treating HIV-1 infection, in combination with other antiretroviral medicines. Raltegravir is the first of a new class of medicines, HIV integrase inhibitors, which block an enzyme the virus needs to multiply. Used with other medicines, it can lower the amount of HIV […]

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Ixempra approved for advanced breast cancer

The US Food and Drug Administration (FDA) has approved Ixempra (ixabepilone), a new anti-cancer treatment for advanced breast cancer, whether or not it has spread, that hasn't responded to other cancer medicines. The approval matters because it gives these patients a new chemotherapy option when other medicines have failed. Ixempra is used in patients who […]

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ADHD medicines in young children: benefits and risks

The Journal of the American Medical Association (JAMA) reported on 17 October 2007 that there is growing evidence that preschool children can benefit from medicines for attention deficit hyperactivity disorder (ADHD), but that their unwanted side effects need watching. In the Preschool ADHD Treatment Study (PATS), side effects occurred more often in preschool children than […]

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