According to a study published in Circulation, a journal of the American Heart Association, healthy men with low testosterone levels are more likely to die from any cause.
The study included 11,606 men aged 40 to 79 who had no cancer or heart disease at the start. Blood samples taken at their first examination were frozen for later analysis. After ten years or more of follow-up, 825 men had died, 369 from cardiovascular disease and 305 from cancer. The researchers analysed the frozen blood of the 825 men who died and compared it with that of 1,489 men who were still alive.
Men with testosterone of 12.5 nmol/L or less were 41% more likely to die than men with 19.5 nmol/L or more. The average level was 16–17 nmol/L, and each 6 nmol/L rise in testosterone was linked with a 14% lower risk of death.
Kay-Tee Khaw, professor of clinical gerontology at the University of Cambridge, said the link between testosterone and heart disease was independent of risk factors such as high blood pressure and obesity. Other studies are needed to confirm the result. Low testosterone may be a marker of poor health rather than a cause, and taking testosterone hasn't been shown to prevent heart disease or death.
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