False blood sugar readings with maltose-containing immunoglobulin

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The US Food and Drug Administration (FDA) has published a report about an elderly patient with diabetes who received an intravenous immunoglobulin product containing 10% maltose. The patient fell into a hypoglycaemic coma with irreversible nerve damage after being given too much insulin, because of a falsely high blood sugar reading.

Some blood glucose meters that use test strips with the enzyme glucose dehydrogenase pyrroloquinolinequinone (GDH-PQQ) can give falsely high readings when the level of maltose in the blood is above 0.9 mmol/L. Patients receiving such products, and the staff caring for them, should use a glucose test that isn't affected by maltose.

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