According to the US Agency for Healthcare Research and Quality (AHRQ), ACE inhibitors and angiotensin receptor blockers (ARBs) work equally well at controlling high blood pressure.
The ACE inhibitors in the review were benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) and trandolapril (Mavik). The ARBs were candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis) and valsartan (Diovan). The findings:
- ACE inhibitors and ARBs controlled blood pressure equally well, based on 16,597 patients followed for 12 weeks to 5 years.
- Dry cough was reported in 1.7% more patients taking ACE inhibitors than ARBs, and patients taking ACE inhibitors were more likely to stop their medicine because of side effects.
- The review looked only at blood pressure control and couldn't compare the risk of death or strokes, which needs longer studies.
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